Waardenburg syndrome
From Felipedia
Waardenburg syndrome is an extensive melanocytopenic hypomelanosis transmitted as an autosomal dominant trait. In the cat, this syndrome demonstrates complete penetrance for hair and skin achromia and incomplete penetrance for degeneration of the internal ear which causes deafness[1]. A genetic mutation has not yet been identified in the cat.
Degenerative lesions of the internal ear appear at the end of the first week of a cat's life and result from an absence of endolymph secretion.
Clinically this syndrome is associated with a white coat, iridal heterochromia or hypochromia and deafness[2].
Differential considerations include vitiligo and piebaldism.
[edit]
