Sebaceous adenoma

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Sebaceous adenoma in a cat with secondary folliculitis
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Sebaceous adenoma in a cat with secondary folliculitis
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Feline sebaceous adenomas are a benign tumor characterized by a preponderance of sebocytes (cells with intracytoplasmic lipid vacuoles) with few basaloid cells and ducts.

Gross Appearance

  • Elevated mass with extensive intradermal component
  • Vary in size from 0.1-0.5 cm in diameter

Histology

  • Well demarcated intradermal mass
  • May extend from the dermo-epidermal interface to the subcutis, replacing the normal tissue
  • Forms discrete lobules, which vary in size
  • May have remnants of dermal collagen within the tumor
  • Variable numbers of basaloid reserve cells and sebocytes
  • Basaloid reserve cells at the periphery of the lobules are from one to several layers in thickness
  • Sebocytes predominate within the tumor
  • Small or larger ducts, often lined by a brightly eosinophilic corrugated squamous epithelium, are often present
  • Neoplastic lobues are not arranged around a distended duct as is found with sebaceous hyperplasia
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