Plasma cell stomatitis

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Plasma cell stomatitis in a DSH cat
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Plasma cell stomatitis in a DSH cat

Plasma cell stomatitis is characterised by painful proliferative lesions on the palatoglossal folds and arches. In cats, it causes anorexia, halitosis, excessive salivation and weight loss, often with associated gingivitis and stomatitis[1].

The lesions have a tendency to ulcerate and bleed. In some studies, FIV infection has been found to be a predisposing factor (15-30% of cases were FIV-positive)[2]. This was not true for FeLV infection (less than 6% of cases were FeLV-positive)[3].

Lesions are similar to those seen in plasma cell gingivitis in many HIV patients. Failure of the immunological barrier of the oral cavity may be induced by certain viruses (e.g. FIV and FCV) and pathogenic periodontal bacteria (e.g. Porphyromonas spp), often present in huge numbers in periodontal disease. This failure could explain some features of the pathophysiology of plasma cell stomatitis. It has also been reported that odontoclastic resorptions were more common in FIV-positive cats[4].

References

  1. Guaguere, E & Prelaud, P (2000) A practical guide to feline dermatology. Merial, France
  2. Knowles, JD Gaskell, RM & Gaskell, CJ (1989) Vet Record 124:336-338
  3. White, SD et al (1992) JAVMA 200:1377-1380
  4. Hofmann-Lehmann, R et al (1998) Vet Immunol Immunopathol 65:299-308
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