Neurofibrosarcoma

From Felipedia

A neurofibrosarcoma (or malignant schwannoma) is a rare cancer of cats caused by an infiltrative spindle cell tumor thought to arise from Schwann cells, perineural fibroblasts, or both. They are a rare variant of the feline fibrosarcoma complex.

Gross Appearance

• Tumor resembles a fibrosarcoma

Histology

• Tumor cells resemble that seen in neurofibromas with differentiation to peripheral nerve sheath fascicles
• Increased pleomorphism and hyperchromatism
• Mitotic figures may be found